Nature Medicine
- 12, 961 - 966 (2006)
Published online: 30 July 2006; | doi:10.1038/nm1433
ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilliNikos Tapinos, Makoto Ohnishi & Anura Rambukkana Supplementary Fig. 1 (pdf 608K)
Rat and human Schwann cells do not induce apoptosis after M. leprae treatment. Supplementary Fig. 2 (pdf 2M)
M. leprae directly bind to extracellular domain of ErbB2 receptor. Supplementary Fig. 3 (pdf 260K)
Human primary Schwann cell proliferation induced by the cell attachment of M. leprae is inhibited by Herceptin antibody 4D5. Supplementary Fig. 4 (pdf 1M)
Relationship of M. leprae binding to ErbB2 with laminin-2 on myelinating Schwann cell–axon units. Supplementary Fig. 5 (pdf 2M)
PKI-166 alone does not affect myelin sheath in vivo. Supplementary Methods (pdf 152K) Supplementary Note (pdf 84K)
| 
