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Nature Medicine - 12, 933 - 938 (2006)
Published online: 23 July 2006; | doi:10.1038/nm1444

Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression

Sucharita Bandyopadhyay, Rui Zhan, Asok Chaudhuri, Misako Watabe, Sudha K Pai, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Yukio Takano, Ken Saito, Mary E Pauza, Sunao Hayashi, Ying Wang, Sonia Mohinta, Tomoyuki Mashimo, Megumi Iiizumi, Eiji Furuta & Kounosuke Watabe

 
Figure 1 thumbnailFigure 1.
KAI1 interacts with DARC in vitro.

Full FigureFull Figure and legend (55K)		 Figure 2 thumbnailFigure 2.
Interaction of KAI1 and DARC leads to growth arrest of cancer cells.

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Figure 3 thumbnailFigure 3.
KAI1 does not suppress spontaneous lung metastasis in DARC knockout mice.

Full FigureFull Figure and legend (47K)		 Table 1 thumbnailTable 1.
Spontaneous and experimental metastases of B16BL6/KAI1 cells in DARC knockout mice

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