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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Medicine - 12, 884 - 885 (2006) doi:10.1038/nm0806-884 Turning neurogenesis up a Notch David A Greenberg & Kunlin Jin The authors are at the Buck Institute for Age Research, Novato, California 94945, USA. dgreenberg@buckinstitute.org kanjiThe key developmental regulator Notch was first characterized in flies but has since been implicated in diseases ranging from cancer to migraine. Experiments in a rat model now suggest that activation of Notch can also promote neurogenesis and healing after stroke. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated. RESEARCH Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo Journal of Cerebral Blood Flow & Metabolism Original Article Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1 Journal of Cerebral Blood Flow & Metabolism Original Article Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke Nature Neuroscience Article (01 Mar 2009) Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal Nature Cell Biology Letter (01 Jul 2009) See all 12 matches for Research  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Rights and permissions Order commercial reprints Save this link Figures & Tables Export citation Open Innovation Challenges Methods of Modeling Adaptation in Populations Deadline: Dec 30 2009 Reward: $15,000 USD The analysis of adaptation with a population is a frequently encountered computational modeling scen... Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... More Challenges Powered by: nature jobs Senior Scientific Manager / Chief Scientific Manager for Metabolic Disorder and Cardiavascular Area In Vivo Pharmacology / Biology Syngene International Bangalore, Karnataka 560099 India Faculty Positions Wayne State University Detroit MI United States More science jobs Post a job for free Search buyers guide:

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