Nature Medicine 12, 824 - 828 (2006)
Published online: 11 June 2006; | doi:10.1038/nm1418
Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophreniaChang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E Gur, Wade H Berrettini, Kalindi Bakshi, Joshua Kamins, Karin E Borgmann-Winter, Steven J Siegel, Robert J Gallop
& Steven E Arnold Supplementary Fig. 1 (pdf 52K) NRG1 or NMDA stimulation activates intracellular signal transduction in postmortem brains. Supplementary Fig. 2 (pdf 68K) NRG1 stimulation induces erbB4 activation in mouse brains at varied postmortem intervals. Supplementary Fig. 3 (pdf 68K) Haloperidol treatment does not enhance NRG1 induced erbB4 activation. Supplementary Fig. 4 (pdf 56K) Association of erbB4 with NMDAR is enhanced in PFCs of SCZ subjects. Supplementary Fig. 5 (pdf 52K) Association of PSD-95 with NMDAR is enhanced in the PFC of SCZ subjects. Supplementary Fig. 6 (pdf 160K) ErbB4 expression in human postmortem brains. Supplementary Table 1 (pdf 72K) Demographic information on the subjects of postmortem brains. Supplementary Note (pdf 156K)
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