Plaques and tangles populate the brains of people with Alzheimer disease. A mouse model that contains both of these lesions is providing insights into how the proteins that make up these hallmarks of the disease interact.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Kim Caesar
References
Games, D. et al. Nature 373, 523–527 (1995).
Hsiao, K. et al. Science 274, 99–102 (1996).
Holcomb, L. et al. Nat. Med. 4, 97–100 (1998).
Lewis, J. et al. Nat. Genet. 25, 402–405 (2000).
Oddo, S. et al. Neuron 39, 409–421 (2003).
Billings, L.M., Oddo, S., Green, K.N., McGaugh, J.L. & LaFerla, F.M. Neuron 45, 675–688 (2005).
Walsh, D.M. et al. Nature 416, 535–539 (2002).
Oddo, S., Billings, L., Kesslak, J.P., Cribbs, D.H. & LaFerla, F.M. Neuron 43, 321–332 (2004).
Oddo, S., Caccamo, A., Smith, I.F., Green, K.N. & Laferla, F.M. Am. J. Pathol. 168, 184–194 (2006).
Lesne, S. et al. Nature 440, 352–357 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Cole, G. A transgenic triple scores a home run. Nat Med 12, 762–763 (2006). https://doi.org/10.1038/nm0706-762
Issue Date:
DOI: https://doi.org/10.1038/nm0706-762
