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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Sponsors Sponsor's Foreword Contents Introduction News News and Views Commentary Market Analysis Nature Medicine - 12, 760 - 761 (2006) doi:10.1038/nm0706-760 A star: a light onto synaptic dysfunction? Seong-Hun Kim, Ya-Ping Tang & Sangram S Sisodia Seong-Hun Kim and Sangram S. Sisodia are in the Department of Neurobiology, Pharmacology & Physiology, and Ya-Ping Tang is in the Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA. ssisodia@bsd.uchicago.edu kanjiLearning and memory is impaired in a mouse model of Alzheimer disease. An A 12-mer called A* may be responsible for these cognitive deficits. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated. NEWS AND VIEWS Alzheimer's disease A needle from the haystack Nature News and Views (16 Mar 2006) A transgenic triple scores a home run Nature Medicine News and Views (01 Jul 2006) See all 4 matches for News And Views RESEARCH Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice The EMBO Journal Article (09 Jan 2008) Natural oligomers of the amyloid-β protein specifically disrupt cognitive function Nature Neuroscience Article (01 Jan 2005)  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Rights and permissions Order commercial reprints Save this link Figures & Tables Export citation Open Innovation Challenges Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... Optimizing Sub-cellular Localization Tags Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... More Challenges Powered by: nature jobs Postdoctoral Position Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 Manager-SCI Indegene Lifesystems Pvt. Ltd Bengaluru 560 071 India More science jobs Post a job for free Search buyers guide:

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