Nature Medicine 12, 677 - 681 (2006)
Published online: 21 May 2006; | doi:10.1038/nm1406
Synaptic scaffolding protein Homer1a protects against chronic inflammatory painAnke Tappe, Matthias Klugmann, Ceng Luo, David Hirlinger, Nitin Agarwal, Justus Benrath, Markus U Ehrengruber, Matthew J During
& Rohini Kuner Supplementary Fig. 1 (pdf 140K)
Specificity controls for antibodies to Homer1 variants and mRNA expression in rat dorsal root ganglia. Supplementary Fig. 2 (pdf 168K)
Demonstration of spinal knockdown of Homer1a using AAV virions expressing shRNA targeted against Homer1a and EGFP bicistronically. Supplementary Fig. 3 (pdf 28K)
Analysis of mice injected with AAV1/2 virions expressing Homer1a, Homer1c, EGFP, Homer1a shRNA or control shRNA in the superficial spinal parenchyma for basal nociceptive sensitivity and motor performance. Supplementary Fig. 4 (pdf 188K)
Analysis of calcium responses in spinal neurons expressing Homer1 or EGFP via either SFV or AAV virions in dissociated cultures or spinal slices. Supplementary Table 1 (pdf 20K)
Comparison of relative levels of expression of Homer proteins induced by nociceptive activity or by AAV-mediated expression in spinal dorsal horn. Supplementary Methods (pdf 80K)
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