Nature Medicine
- 12, 608 - 609 (2006)
doi:10.1038/nm0606-608
Cannabinoids hurt, heal in cirrhosisGeorge Kunos, Douglas Osei-Hyiaman, Sándor Bátkai & Bin Gao
The authors are in the Laboratory of Physiologic Studies, National Institute on Alcohol Abuse & Alcoholism, National Institutes of Health, Bethesda, Maryland 20892-9413, USA.
gkunos@mail.nih.gov
kanjiMarijuana receptors are present in fibrogenic cells of the liver, and their expression is induced in cirrhosis. Blockade of the CB1 subtype is now shown to inhibit fibrogenesis, offering a new approach for the treatment of cirrhosis (pages 671 – 676).
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