Nature Medicine
- 12, 511 - 512 (2006)
doi:10.1038/nm0506-511
Overcoming insulin resistance with CNTF
Rexford S Ahima
The author is in the Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. ahima@mail.med.upenn.edu
kanjiCiliary neurotrophic factor (CNTF) enhances fatty-acid oxidation in muscle and reduces insulin resistance in obese, diabetic mice. Because skeletal muscle is the major site of insulin-mediated glucose uptake, this action of CNTF could benefit individuals with diabetes (pages 541–548).
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