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Nature Medicine
ISSUE
April 2006, Volume 12 No 4
Editorial
News
Correspondence
Book Review
News and Views
Brief Communications
Articles
Letters
Technical Reports
Addendum
About the cover
Editorial Top
Denying science p369
doi:10.1038/nm0406-369
Full text | PDF (67K)
News Top
Failed prevention trials leave behind bounty of samples p371
Meredith Wadman
Published online: 29 March 2006 | doi:10.1038/nm0406-371
Abstract | Full text | PDF (187K)
With scores still infected, India declares leprosy 'eliminated' p372
T V Padma
Published online: 29 March 2006 | doi:10.1038/nm0406-372a
Abstract | Full text | PDF (121K)
British trial disaster casts doubts on testing guidelines p372
Meredith Wadman
Published online: 29 March 2006 | doi:10.1038/nm0406-372b
Abstract | Full text | PDF (121K)
Swedish students protest proposal to cut PhD terms p373
Charlotte Schubert
Published online: 29 March 2006 | doi:10.1038/nm0406-373a
Abstract | Full text | PDF (141K)
US drug approval ignores science's subtleties, experts say p373
Emily Waltz
Published online: 29 March 2006 | doi:10.1038/nm0406-373b
Abstract | Full text | PDF (141K)
Addictive drugs still best option for attention deficit disorder p374
Paroma Basu
Published online: 29 March 2006 | doi:10.1038/nm0406-374a
Abstract | Full text | PDF (141K)
Spain takes aim at better clinical research schemes p374
Xavier Bosch
Published online: 29 March 2006 | doi:10.1038/nm0406-374b
Abstract | Full text | PDF (141K)
News In Brief p375
doi:10.1038/nm0406-375
Full text | PDF (124K)
News Feature: Drugs down the drain pp376 - 377
Alan Dove
Published online: 29 March 2006 | doi:10.1038/nm0406-376
Abstract | Full text | PDF (191K)
Profile: Thomas Frieden p378
Apoorva Mandavilli
Published online: 29 March 2006 | doi:10.1038/nm0406-378
Abstract | Full text | PDF (76K)
Correspondence Top
Reply to 'Side benefits sway developing nations to choose unneeded vaccines' p379
Steven T. Wiersma
doi:10.1038/nm0406-379a
Full text | PDF (60K)
Reply to 'Hormone in the hot seat' pp379 - 380
C. Dominique Toran-Allerand
doi:10.1038/nm0406-379b
Full text | PDF (71K)
Book Review Top
The wake-up call p381
Reviewed by: Michael Stebbins
doi:10.1038/nm0406-381
Full text | PDF (73K)
News and Views Top
Stem cell aging: what bleach can teach pp383 - 384
Jie Liu & Toren Finkel
doi:10.1038/nm0406-383
Abstract | Full text | PDF (203K)
See also: Letter by Ito et al.
Streptococcus moves inward pp384 - 386
P Patrick Cleary
doi:10.1038/nm0406-384
Abstract | Full text | PDF (259K)
Inserting optimism into gene therapy pp386 - 388
Luigi Naldini
doi:10.1038/nm0406-386
Abstract | Full text | PDF (184K)
See also: Article by Ott et al.
Fighting infections with vitamin D pp388 - 390
Michael Zasloff
doi:10.1038/nm0406-388
Abstract | Full text | PDF (1,202K)
Remodeling after stroke pp390 - 391
Berislav V Zlokovic
doi:10.1038/nm0406-390
Abstract | Full text | PDF (599K)
See also: Letter by Zhao et al.
Remodeling in the kidney p391
Charlotte Schubert
doi:10.1038/nm0406-391
Full text | PDF (144K)
Protein twists and turns in Alzheimer disease pp392 - 393
Stuart Maudsley & Mark P Mattson
doi:10.1038/nm0406-392
Abstract | Full text | PDF (425K)
Research Highlights p394
doi:10.1038/nm0406-394
Full text | PDF (75K)
Brief Communications Top
Human sebaceous tumors harbor inactivating mutations in LEF1 pp395 - 397
Hikaru Takeda, Stephen Lyle, Alexander J F Lazar, Christos C Zouboulis, Ian Smyth & Fiona M Watt
Published online: 26 March 2006 | doi:10.1038/nm1386
Abstract | Full text | PDF (265K)  | Supplementary Information
Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis pp398 - 400
Stephane Decramer, Stefan Wittke, Harald Mischak, Petra Zürbig, Michael Walden, François Bouissou, Jean-Loup Bascands & Joost P Schanstra
Published online: 19 March 2006 | doi:10.1038/nm1384
Abstract | Full text | PDF (175K)  | Supplementary Information
Articles Top
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1 pp401 - 409
Marion G Ott, Manfred Schmidt, Kerstin Schwarzwaelder, Stefan Stein, Ulrich Siler, Ulrike Koehl, Hanno Glimm, Klaus Kühlcke, Andrea Schilz, Hana Kunkel, Sonja Naundorf, Andrea Brinkmann, Annette Deichmann, Marlene Fischer, Claudia Ball, Ingo Pilz, Cynthia Dunbar, Yang Du, Nancy A Jenkins, Neal G Copeland, Ursula Lüthi, Moustapha Hassan, Adrian J Thrasher, Dieter Hoelzer, Christof von Kalle, Reinhard Seger & Manuel Grez
Published online: 02 April 2006 | doi:10.1038/nm1393
Abstract | Full text | PDF (1,184K)  | Supplementary Information
See also: News and Views by Naldini
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells pp410 - 416
Ju-Seog Lee, Jeonghoon Heo, Louis Libbrecht, In-Sun Chu, Pal Kaposi-Novak, Diego F Calvisi, Arsen Mikaelyan, Lewis R Roberts, Anthony J Demetris, Zongtang Sun, Frederik Nevens, Tania Roskams & Snorri S Thorgeirsson
Published online: 12 March 2006 | doi:10.1038/nm1377
Abstract | Full text | PDF (536K)  | Supplementary Information
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants pp417 - 424
Thorbald van Hall, Elisabeth Z Wolpert, Peter van Veelen, Sandra Laban, Michael van der Veer, Marjet Roseboom, Sandra Bres, Per Grufman, Arnoud de Ru, Hugo Meiring, Ad de Jong, Kees Franken, Antoinette Teixeira, Rob Valentijn, Jan Wouter Drijfhout, Frits Koning, Marcel Camps, Ferry Ossendorp, Klas Kärre, Hans-Gustaf Ljunggren, Cornelis J M Melief & Rienk Offringa
Published online: 19 March 2006 | doi:10.1038/nm1381
Abstract | Full text | PDF (331K)  | Supplementary Information
Induction of leptin resistance through direct interaction of C-reactive protein with leptin pp425 - 432
Ke Chen, Fanghong Li, Ji Li, Hongbo Cai, Steven Strom, Alessandro Bisello, David E Kelley, Miriam Friedman-Einat, Gregory A Skibinski, Mark A McCrory, Alexander J Szalai & Allan Z Zhao
Published online: 02 April 2006 | doi:10.1038/nm1372
Abstract | Full text | PDF (389K)  | Supplementary Information
Newly expressed SUR1-regulated NCCa-ATP channel mediates cerebral edema after ischemic stroke pp433 - 440
J Marc Simard, Mingkui Chen, Kirill V Tarasov, Sergei Bhatta, Svetlana Ivanova, Ludmila Melnitchenko, Natalya Tsymbalyuk, G Alexander West & Volodymyr Gerzanich
Published online: 19 March 2006 | doi:10.1038/nm1390
Abstract | Full text | PDF (645K)
Letters Top
Role of matrix metalloproteinases in delayed cortical responses after stroke pp441 - 445
Bing-Qiao Zhao, Sophia Wang, Hahn-Young Kim, Hannah Storrie, Bruce R Rosen, David J Mooney, Xiaoying Wang & Eng H Lo
Published online: 26 March 2006 | doi:10.1038/nm1387
Abstract | Full text | PDF (506K)  | Supplementary Information
See also: News and Views by Zlokovic
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells pp446 - 451
Keisuke Ito, Atsushi Hirao, Fumio Arai, Keiyo Takubo, Sahoko Matsuoka, Kana Miyamoto, Masako Ohmura, Kazuhito Naka, Kentaro Hosokawa, Yasuo Ikeda & Toshio Suda
Published online: 26 March 2006 | doi:10.1038/nm1388
Abstract | Full text | PDF (314K)  | Supplementary Information
See also: News and Views by Liu & Finkel
Technical Reports Top
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts pp452 - 458
Wolfram-Hubertus Zimmermann, Ivan Melnychenko, Gerald Wasmeier, Michael Didié, Hiroshi Naito, Uwe Nixdorff, Andreas Hess, Lubos Budinsky, Kay Brune, Bjela Michaelis, Stefan Dhein, Alexander Schwoerer, Heimo Ehmke & Thomas Eschenhagen
Published online: 02 April 2006 | doi:10.1038/nm1394
Abstract | Full text | PDF (544K)  | Supplementary Information
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction pp459 - 465
Yoshinori Miyahara, Noritoshi Nagaya, Masaharu Kataoka, Bobby Yanagawa, Koichi Tanaka, Hiroyuki Hao, Kozo Ishino, Hideyuki Ishida, Tatsuya Shimizu, Kenji Kangawa, Shunji Sano, Teruo Okano, Soichiro Kitamura & Hidezo Mori
Published online: 02 April 2006 | doi:10.1038/nm1391
Abstract | Full text | PDF (665K)  | Supplementary Information
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I pp466 - 472
Hideki Hasegawa, Hirofumi Sawa, Martha J Lewis, Yasuko Orba, Noreen Sheehy, Yoshie Yamamoto, Takeshi Ichinohe, Yasuko Tsunetsugu-Yokota, Harutaka Katano, Hidehiro Takahashi, Junichiro Matsuda, Tetsutaro Sata, Takeshi Kurata, Kazuo Nagashima & William W Hall
Published online: 19 March 2006 | doi:10.1038/nm1389
Abstract | Full text | PDF (1,090K)  | Supplementary Information
A sensitive and high-throughput assay to detect low-abundance proteins in serum pp473 - 477
Hongtao Zhang, Xin Cheng, Mark Richter & Mark I Greene
Published online: 12 March 2006 | doi:10.1038/nm1378
Abstract | Full text | PDF (205K)
Addendum Top
ADDENDUM: Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease p479
S S Gill, N K Patel, G R Hotton, K O'Sullivan, R McCarter, M Bunnage, D J Brooks, C N Svendsen & P Heywood
doi:10.1038/nm0406-479
Full text | PDF (57K)
  Top
 
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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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