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Nature Medicine 12, 441 - 445 (2006)
Published online: 26 March 2006; | doi:10.1038/nm1387

Role of matrix metalloproteinases in delayed cortical responses after stroke

Bing-Qiao Zhao, Sophia Wang, Hahn-Young Kim, Hannah Storrie, Bruce R Rosen, David J Mooney, Xiaoying Wang & Eng H Lo

 
Figure 1 thumbnailFigure 1.
Increased expression of cortical MMP-9 during stroke recovery.

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 Figure 2 thumbnailFigure 2.
MMP activity after stroke, as measured by in situ zymography.

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Figure 3 thumbnailFigure 3.
Upregulation of RECA-1 and Egr1 within peri-infarct cortical areas precedes cell death.

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 Figure 4 thumbnailFigure 4.
Worsening of delayed stroke outcomes by inhibition of MMPs.

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