Nature Medicine
- 12, 392 - 393 (2006)
doi:10.1038/nm0406-392
Protein twists and turns in Alzheimer disease
Stuart Maudsley & Mark P Mattson
The authors are in the Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, Maryland 21224, USA. maudsleyst@grc.nia.nih.gov
kanjiAn enzyme that modifies protein structure seems to help keep Alzheimer disease at bay. The enzyme affects two proteins thought to be key to disease pathology: amyloid precursor protein (APP) and the microtubule-binding protein tau.
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