Nature Medicine 12, 354 - 360 (2006)
Published online: 26 February 2006; | doi:10.1038/nm1368
Viral nanoparticles as tools for intravital vascular imagingJohn D Lewis, Giuseppe Destito, Andries Zijlstra, Maria J Gonzalez, James P Quigley, Marianne Manchester
& Heidi Stuhlmann Supplementary Fig. 1 (pdf 132K)
Cell adhesion and uptake is inhibited by coating of CPMV with PEG. Supplementary Fig. 2 (pdf 144K)
CPMV uptake is eliminated in chick embryos and reduced significantly in adult mice by PEG coating. Supplementary Video 1 (avi 8M)
Fluorescent timelapse imaging of yolk sac of 11.5 d mouse embryo at 10 magnification 1 h after CPMV-A555 perfusion. Supplementary Video 2 (avi 4M)
Fluorescent timelapse imaging of chick embryo CAM vasculature at 20 magnification 30 min after CPMV-A555 perfusion. Supplementary Video 3 (avi 6M)
Fluorescent timelapse imaging of chick embryo CAM vasculature at 10 magnification 30 min after CPMV-A555 (left) and CPMV-PEG-FITC (right) coperfusion, duration; 11 s. Supplementary Video 4 (avi 10M)
Fluorescent timelapse imaging of internal vasculature of 11.5 d mouse embryo at 10 magnification 1 h after CPMV-A555 perfusion. Supplementary Methods (pdf 40K)
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