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Nature Medicine 12, 273 - 274 (2006)
doi:10.1038/nm0306-273

Islets break off from the mainland

J Michael Rukstalis1 & Joel F Habener1

  1. The authors are in the Laboratory of Molecular Endocrinology, Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. e-mail: jmrukstalis@partners.org or e-mail: jhabener@partners.org


A generous source of insulin-producing cells is found in the pancreas, raising hopes for transplantation therapies for diabetes (pages 310–316).


Insulin-producing cells can arise from run-of-the mill epithelial tissue in the pancreas, suggests a study in this issue by Hao et al.1. Such tissue could potentially provide a source of material for transplantation therapies for diabetes, an approach currently plagued by a shortage of transplantable cells.

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