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Nature Medicine 12, 235 - 239 (2006)
Published online: 5 February 2006; | doi:10.1038/nm1351

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

Ulrike Fiedler, Yvonne Reiss, Marion Scharpfenecker, Verena Grunow, Stefanie Koidl, Gavin Thurston, Nicholas W Gale, Martin Witzenrath, Simone Rosseau, Norbert Suttorp, Astrid Sobke, Matthias Herrmann, Klaus T Preissner, Peter Vajkoczy & Hellmut G Augustin

 
Figure 1 thumbnailFigure 1.
Thioglycollate-induced peritonitis and S. aureus infection experiments.

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Intravital microscopy analysis of rolling and adhering leukocytes after TNF-alpha stimulation in the dorsal skinfold chamber model.

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Figure 3 thumbnailFigure 3.
Ang-2–mediated sensitization of endothelial cells to TNF-alpha–induced monocyte adhesion and expression of cell adhesion molecules.

Full FigureFull Figure and legend (67K)		 Figure 4 thumbnailFigure 4.
Expression of ICAM-1 on HUVECs.

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