Nature Medicine
- 12, 168 - 169 (2006)
doi:10.1038/nm0206-168
Oxygen deprivation provokes melanomaAmy E Adams1, Yakov Chudnovsky1 & Paul A Khavari1, 21
The authors are in the Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
2
Paul A. Khavari is also in the Veterans Affairs Palo Alto Healthcare System, Palo Alto, California 94304, USA. khavari@cmgm.stanford.edu
kanjiMelanoma may be promoted by low oxygen conditions in the skin, which turn on the oxygen-response regulator HIF-1. HIF-1 seems to act in concert with well-established oncoproteins to promote tumorigenesis—a process that responds to the drug rapamycin.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
