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Fat fuels insulin resistance through Toll-like receptors

Nature Medicine volume 12, pages 1359–1361 (2006)Cite this article

Dietary lipids seem to activate a Toll-like receptor, which is better known for its defense against infectious pathogens. The findings suggest that the resulting inflammatory response may link obesity with type 2 diabetes.

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Figure 1: TLR4 and insulin resistance.

Ann Thomson

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Authors and Affiliations

  1. Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio, USA

    Matthias Tschöp

  2. Department of Genome Sciences, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio, USA

    George Thomas

Authors
  1. Matthias Tschöp
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  2. George Thomas
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Tschöp, M., Thomas, G. Fat fuels insulin resistance through Toll-like receptors. Nat Med 12, 1359–1361 (2006). https://doi.org/10.1038/nm1206-1359

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