Nature Medicine
- 12, 1356 - 1358 (2006)
doi:10.1038/nm1206-1356
Osteoclasts, no longer osteoblast slavesBrendan F Boyce & Lianping Xing
The authors are in the Department of Pathology and Laboratory Medicine and the Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA. brendan_boyce@urmc.rochester.edu
kanjiA protein has been identified that promotes the formation of osteoclasts, bone-degrading cells—while also inhibiting osteoblasts, bone-forming cells. The findings could lead to new avenues of drug development to strengthen bone (pages 1403–1409).
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