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News and Views
Nature Medicine - 12, 1351 - 1352 (2006)
doi:10.1038/nm1206-1351

Gut microbes out of control in HIV infection

Barton F Haynes

The author is at the Duke Human Vaccine Institute, Center for HIV-AIDS Vaccine Immunology, Duke University School of Medicine, Circuit Drive, Durham, North Carolina 27710, USA. haynes002@mc.duke.edu.

kanjiHIV-1 infection results in chronic activation of the immune system—a process that is thought to contribute to T-cell depletion and progression to AIDS. Chronic activation is now suggested to occur through a breakdown of the mucosal barrier and stimulation of immune cells by microbial products (pages 1365–1371).

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ISSN: 1078-8956
EISSN: 1546-170X
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