The goal of replacing dying cells in Parkinson disease with stem cells is now brought a step closer to the clinic. A new protocol eases symptoms in a rat model of the disease, but also raises the concern that poorly differentiated cells have the potential to become tumorigenic (pages 1259–1268).
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References
Brederlau, A. et al. Stem Cells 24, 1433–1440 (2006).
Park, C.H. et al. J. Neurochem. 92, 1265–1276 (2005).
Martin, M.J., Muotri, A., Gage, F. & Varki, A. Nat. Med. 11, 228–232 (2005).
Roy, N.S. et al. Nat. Med. 12, 1259–1268 (2006).
Clarkson, E.D. & Freed, C.R. Life Sci. 65, 2427–2437 (1999).
Takeshima, T., Johnston, J.M. & Commissiong, J.W. J. Neurosci. 14, 4769–4779 (1994).
Wagner, J. et al. Nat. Biotechnol. 17, 653–659 (1999).
Lee, S.H., Lumelsky, N., Studer, L., Auerbach, J.M. & McKay, R.D. Nat. Biotechnol. 18, 675–679 (2000).
Yu, R.K. & Yanagisawa, M. CNS Neurol. Disord. Drug Targets 5, 415–423 (2006).
Andersson, E. et al. Cell 124, 393–405 (2006).
Martinat, C. et al. Proc. Natl. Acad. Sci. USA 103, 2874–2879 (2006).
Fukuda, H. et al. Stem Cells 24, 763–771 (2006).
Yan, Y. et al. Stem Cells 23, 781–790 (2005).
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Carson, C., Aigner, S. & Gage, F. Stem cells: the good, bad and barely in control. Nat Med 12, 1237–1238 (2006). https://doi.org/10.1038/nm1106-1237
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DOI: https://doi.org/10.1038/nm1106-1237
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