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Letter
Nature Medicine - 12, 1175 - 1180 (2006)
Published online: 24 September 2006; | doi:10.1038/nm1489

Requirement for CD44 in homing and engraftment of BCR-ABL–expressing leukemic stem cells

Daniela S Krause, Katherine Lazarides, Ulrich H von Andrian & Richard A Van Etten

Supplementary Fig. 1 (pdf 88K)
Serial flow cytometric analysis of peripheral blood from a representative WT recipient of BCR-ABL1–transduced Cd44-/- BM that did not develop fatal CML-like leukemia.

Supplementary Fig. 2 (pdf 92K)
Flow cytometric analysis of primary B-lymphoid progenitors from WT or Cd44-/- (CD44 KO) donors, transformed in vitro (Roumiantsev et al., Blood 97, 4–13 (2001)) with retrovirus co-expressing BCR-ABL and either GFP (B-A + GFP) or human CD44s (B-A + huCD44).

Supplementary Table 1 (pdf 40K)
Quantitation of engrafting proviral clones in leukemic cohorts.


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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