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Article
Nature Medicine - 12, 1160 - 1166 (2006)
Published online: 24 September 2006; | doi:10.1038/nm1475

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals

Ann M Leen, G Doug Myers, Uluhan Sili, M Helen Huls, Heidi Weiss, Kathryn S Leung, George Carrum, Robert A Krance, Chung-Che Chang, Jeffrey J Molldrem, Adrian P Gee, Malcolm K Brenner, Helen E Heslop, Cliona M Rooney & Catherine M Bollard

Supplementary Fig. 1 (pdf 232K)
Effects of adenovirus-specific CTL in vivo.

Supplementary Fig. 2 (pdf 144K)
Activity of polyclonal CTL line for a representative patient, sorted for both CD4+ and CD8+ T cells against CMV.

Supplementary Table 1 (pdf 60K)
Virus-specific activity of CTL lines.

Supplementary Table 2 (pdf 60K)
Epitopes recognized in each virus by multivirus-specific CTL compared to monospecific CTL.


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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