The interplay of factors that impair insulin signaling to cause type 2 diabetes is unclear, but one idea is that visceral fat might produce them. Visfatin, a protein previously known for its effect on immune cells, may be one of these factors.
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Murphy, K., Bloom, S. Are all fats created equal?. Nat Med 12, 32–33 (2006). https://doi.org/10.1038/nm0106-32
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DOI: https://doi.org/10.1038/nm0106-32
