Nature Medicine
- 12, 43 - 44 (2006)
doi:10.1038/nm0106-43
The humoral side of insulin resistanceMitchell A Lazar
The author is in the Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6149, USA. lazar@mail.med.upenn.edu
kanjiPrimary alterations in insulin signaling pathways are not the only way to reduce the body's sensitivity to insulin. By promoting the release of cytokines, liver inflammation can also lead to insulin resistance.
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