Nature Medicine
11, 861 - 866 (2005)
Published online: 10 July 2005; | doi:10.1038/nm1278
Thiazolidinediones expand body fluid volume through PPAR stimulation of ENaC-mediated renal salt absorptionYouFei Guan, Chuanming Hao, Dae Ryong Cha, Reena Rao, Wendell Lu, Donald E Kohan, Mark A Magnuson, Reyadh Redha, Yahua Zhang
& Matthew D Breyer Supplementary Fig. 1 (pdf 64K) Location of candidate PPREs in mouse ENaC intron 1 sequence. Supplementary Table 1 (pdf 73K) Length, weight and serum chemistries for AQP2Cre Pparg
flox/flox mice and Pparg wild-type mice (wt). Supplementary Table 2 (pdf 56K) Electrophysiologic characterization and ion transport rates of Transwell® culture mouse IMCD cell monolayers. Supplementary Table 3 (pdf 68K) Sequences used to search TESS for PPREs in mouse Scnn1 genes. Supplementary Methods (pdf 179K)
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