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News and Views
Nature Medicine 11, 720 - 721 (2005)
doi:10.1038/nm0705-720
A single shot against Ebola and Marburg virus
Sylvain Baize1
- The author is in the Unité de Biologie des Infections Virales Emergentes, Institut Pasteur, IFR128 Biosciences Lyon-Gerland, Lyon, France. e-mail: baize@cervi-lyon.inserm.fr
Abstract
New vaccines protect monkeys from Ebola and Marburg virus infections after a single shot. The live vaccines are built using a virus platform that should allow widespread protection in people, if the approach holds up in later safety and efficacy studies (pages 786–790).
There are no approved vaccines or effective drugs against Ebola or Marburg viruses. These filoviruses induce dramatic hemorrhagic fever—killing between 40% and 90% of infected individuals within 1–2 weeks after disease onset, depending on the virus species1.
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