Nature Medicine
11, 551 - 555 (2005)
Published online: 24 April 2005; | doi:10.1038/nm1239
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer diseaseMark H Tuszynski, Leon Thal, Mary Pay, David P Salmon, Hoi Sang U, Roy Bakay, Piyush Patel, Armin Blesch, H Lee Vahlsing, Gilbert Ho, Gang Tong, Steven G Potkin, James Fallon, Lawrence Hansen, Elliott J Mufson, Jeffrey H Kordower, Christine Gall
& James ConnerSupplementary Fig. 1 (pdf 38K)
Using immunoelectrophoresis and comparison to known quantities of loaded proNGF and NGF, the ratio of proNGF:NGF was less than 1:100.
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