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Letter
Nature Medicine  11, 567 - 571 (2005)
Published online: 10 April 2005; | doi:10.1038/nm1227

Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action

Emilie A Bard-Chapeau, Andrea L Hevener, Shinong Long, Eric E Zhang, Jerrold M Olefsky & Gen-Sheng Feng

Supplementary Fig. 1 (pdf 58K)
Insulin-induced tyrosine phosphorylation of IRbeta in LGKO liver.

Supplementary Fig. 2 (pdf 49K)
Normal expression levels of proteins involved in insulin signalling.

Supplementary Fig. 3 (pdf 50K)
Deletion of Gab1 leads to enhanced insulin signalling through IRS-1, -2 in hepatocytes.

Supplementary Table 1 (pdf 21K)
Characteristics of mutant mice at 2 and 12 months of age


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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