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Article
Nature Medicine  11, 400 - 408 (2005)
Published online: 20 March 2005; | doi:10.1038/nm1214

Angiopoietin-related growth factor antagonizes obesity and insulin resistance

Yuichi Oike, Masaki Akao, Kunio Yasunaga, Toshimasa Yamauchi, Tohru Morisada, Yasuhiro Ito, Takashi Urano, Yoshishige Kimura, Yoshiaki Kubota, Hiromitsu Maekawa, Takeshi Miyamoto, Keishi Miyata, Shun-ichiro Matsumoto, Juro Sakai, Naomi Nakagata, Motohiro Takeya, Haruhiko Koseki, Yoshihiro Ogawa, Takashi Kadowaki & Toshio Suda

Supplementary Fig. 1 (pdf 59K)
Gene targeting of the AGF locus.

Supplementary Fig. 2 (pdf 74K)
Generation of AGF-transgenic mice.

Supplementary Fig. 3 (pdf 71K)
AGF-stimulated intracellular signaling in C2C12 myocytes.

Supplementary Fig. 4 (pdf 34K)
Impaired blood flow perfusion in AGF-/- females.

Supplementary Fig. 5 (pdf 33K)
Increased insulin sensitivity in K14-AGF-transgenic mice7, 8 despite a loss of WAT mass.

Supplementary Table 1 (pdf 16K)

Supplementary Methods (pdf 41K)


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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