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Letter
Nature Medicine  11, 418 - 422 (2005)
Published online: 27 March 2005; | doi:10.1038/nm1211

Apolipoprotein M is required for prebold beta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis

Christian Wolfrum, Matthew N Poy & Markus Stoffel

Supplementary Fig. 1 (pdf 56K)
Immunoblot analysis of whole-liver extracts from si-luc− and si-apoM−injected C57BL/6 mice.

Supplementary Fig. 2 (pdf 39K)
Composition of alpha- and prebeta-HDL in human plasma.

Supplementary Fig. 3 (pdf 7K)
Adenoviral apoM overexpression in livers of Ldlr-/- mice.

Supplementary Fig. 4 (pdf 37)
Increased plasma HDL levels in Ldlr-/- mice treated with Ad-apoM.

Supplementary Table 1 (pdf 57K)
HDL-associated cholesterol levels and relative composition of isolated HDL particles in si-apoM− and Ad-apoM−treated C57BL/6 (WT) mice and in Ad-apoM−treated Tcf1-/- mice

Supplementary Table 2 (pdf 36K)
Tissue uptake of 125I-TC-HDL2 from C57BL/6 mice (125I-TC-WT-HDL2), si-apoM−treated mice (125I-TC-si-apoM-HDL2), and Tcf1-/- mice (125I-TC-Tcf1-/--HDL2).

Supplementary Table 3 (pdf 36K)
Plasma concentration of cholesterol, tricglycerides, phospholipids, protein, apoM and apoAI in Ldlr-/- mice.

Supplementary Table 4 (pdf 62K)
Plasma concentrations of cholesterol, triglycerides, phospholipids, protein, apoM and apoAI in experimental animal models.


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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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