Nature Medicine
11, 418 - 422 (2005)
Published online: 27 March 2005; | doi:10.1038/nm1211
Apolipoprotein M is required for pre -HDL formation and cholesterol efflux to HDL and protects against atherosclerosisChristian Wolfrum, Matthew N Poy
& Markus StoffelSupplementary Fig. 1 (pdf 56K) Immunoblot analysis of whole-liver extracts from si-luc−
and si-apoM−injected C57BL/6 mice. Supplementary Fig. 2 (pdf 39K) Composition of - and pre -HDL in human plasma. Supplementary Fig. 3 (pdf 7K) Adenoviral apoM overexpression in livers of Ldlr-/- mice. Supplementary Fig. 4 (pdf 37) Increased plasma HDL levels in Ldlr-/- mice
treated with Ad-apoM. Supplementary Table 1 (pdf 57K) HDL-associated cholesterol levels and relative composition of isolated HDL particles in si-apoM−
and Ad-apoM−treated C57BL/6 (WT) mice and
in Ad-apoM−treated Tcf1-/- mice Supplementary Table 2 (pdf 36K) Tissue uptake of 125I-TC-HDL2 from
C57BL/6 mice (125I-TC-WT-HDL2), si-apoM−treated
mice (125I-TC-si-apoM-HDL2), and Tcf1-/- mice
(125I-TC-Tcf1-/--HDL2). Supplementary Table 3 (pdf 36K) Plasma concentration of cholesterol, tricglycerides, phospholipids, protein, apoM and
apoAI in Ldlr-/- mice. Supplementary Table 4 (pdf 62K) Plasma concentrations of cholesterol, triglycerides, phospholipids, protein, apoM and
apoAI in experimental animal models.
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