Knocking out a stress hormone receptor in the forebrain of mice generates symptoms of depression, which are alleviated by the antidepressant imipramine. The findings begin to unravel the intricate relationship between stress and depression.
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No interaction between serotonin transporter gene (5-HTTLPR) polymorphism and adversity on depression among Japanese children and adolescents
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Akil, H. Stressed and depressed. Nat Med 11, 116–118 (2005). https://doi.org/10.1038/nm0205-116
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DOI: https://doi.org/10.1038/nm0205-116
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