The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milkpp127 - 129 Johan W Jonker, Gracia Merino, Sandra Musters, Antonius E van Herwaarden, Ellen Bolscher, Els Wagenaar, Elly Mesman, Trevor C Dale
& Alfred H Schinkel Published online: 30 January 2005|doi:10.1038/nm1186 Abstract|Full text|PDF
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|Supplementary Information
Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivopp130 - 137 Brent A Hanks, Jianghong Jiang, Rana A K Singh, Weitao Song, Michael Barry, Mary H Huls, Kevin M Slawin
& David M Spencer Published online: 23 January 2005|doi:10.1038/nm1183 Abstract|Full text|PDF
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|Supplementary Information
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune diseasepp138 - 145 Karl S Lang, Mike Recher, Tobias Junt, Alexander A Navarini, Nicola L Harris, Stefan Freigang, Bernhard Odermatt, Curdin Conrad, Lars M Ittner, Stefan Bauer, Sanjiv A Luther, Satoshi Uematsu, Shizuo Akira, Hans Hengartner
& Rolf M Zinkernagel Published online: 16 January 2005|doi:10.1038/nm1176 Abstract|Full text|PDF
(1,467K)
|Supplementary Information See also:News and Views by Bach
Experimental autoimmune encephalomyelitis repressed by microglial paralysispp146 - 152 Frank L Heppner, Melanie Greter, Denis Marino, Jeppe Falsig, Gennadij Raivich, Nadine Hövelmeyer, Ari Waisman, Thomas Rülicke, Marco Prinz, Josef Priller, Burkhard Becher
& Adriano Aguzzi Published online: 23 January 2005|doi:10.1038/nm1177 Abstract|Full text|PDF
(954K)
|Supplementary Information
Spontaneous fetal loss caused by placental thrombosis in estrogen sulfotransferase—deficient micepp153 - 159 Ming Han Tong, Hong Jiang, Ping Liu, John A Lawson, Lawrence F Brass
& Wen-Chao Song Published online: 30 January 2005|doi:10.1038/nm1184 Abstract|Full text|PDF
(1,088K)
|Supplementary Information
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilizationpp160 - 166 Gen Kondoh, Hiromasa Tojo, Yuka Nakatani, Nobuyasu Komazawa, Chie Murata, Kazuo Yamagata, Yusuke Maeda, Taroh Kinoshita, Masaru Okabe, Ryo Taguchi
& Junji Takeda Published online: 23 January 2005|doi:10.1038/nm1179 Abstract|Full text|PDF
(633K)
|Supplementary Information See also:News and Views by Corvol
Accelerated re-epithelialization in 3-integrin-deficient- mice is associated with enhanced TGF-1 signalingpp167 - 174 L E Reynolds, F J Conti, M Lucas, R Grose, S Robinson, M Stone, G Saunders, C Dickson, R O Hynes, A Lacy-Hulbert
& K Hodivala-Dilke Published online: 16 January 2005|doi:10.1038/nm1165 Abstract|Full text|PDF
(1,058K)
|Supplementary Information
Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic micepp175 - 182 Tohru Uchida, Takehiro Nakamura, Naoko Hashimoto, Tomokazu Matsuda, Ko Kotani, Hiroshi Sakaue, Yoshiaki Kido, Yoshitake Hayashi, Keiichi I Nakayama, Morris F White
& Masato Kasuga Published online: 30 January 2005|doi:10.1038/nm1187 Abstract|Full text|PDF
(1,291K)
|Supplementary Information
Local and systemic insulin resistance resulting from hepatic activation of IKK- and NF-Bpp183 - 190 Dongsheng Cai, Minsheng Yuan, Daniel F Frantz, Peter A Melendez, Lone Hansen, Jongsoon Lee
& Steven E Shoelson Published online: 30 January 2005|doi:10.1038/nm1166 Abstract|Full text|PDF
(841K)
|Supplementary Information
IKK- links inflammation to obesity-induced insulin resistancepp191 - 198 Melek C Arkan, Andrea L Hevener, Florian R Greten, Shin Maeda, Zhi-Wei Li, Jeffrey M Long, Anthony Wynshaw-Boris, Giuseppe Poli, Jerrold Olefsky
& Michael Karin Published online: 30 January 2005|doi:10.1038/nm1185 Abstract|Full text|PDF
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Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesitypp199 - 205 Mark W Sleeman, Katherine E Wortley, Ka-Man V Lai, Lori C Gowen, Jennifer Kintner, William O Kline, Karen Garcia, Trevor N Stitt, George D Yancopoulos, Stanley J Wiegand
& David J Glass Published online: 16 January 2005|doi:10.1038/nm1178 Abstract|Full text|PDF
(648K)
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Cathepsin L is required for endothelial progenitor cell−induced neovascularizationpp206 - 213 Carmen Urbich, Christopher Heeschen, Alexandra Aicher, Ken-ichiro Sasaki, Thomas Bruhl, Mohammad R Farhadi, Peter Vajkoczy, Wolf K Hofmann, Christoph Peters, Len A Pennacchio, Nasreddin D Abolmaali, Emmanouil Chavakis, Thomas Reinheckel, Andreas M Zeiher
& Stefanie Dimmeler Published online: 23 January 2005|doi:10.1038/nm1182 Abstract|Full text|PDF
(843K)
|Supplementary Information
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophypp214 - 222 Eiki Takimoto, Hunter C Champion, Manxiang Li, Diego Belardi, Shuxun Ren, E Rene Rodriguez, Djahida Bedja, Kathleen L Gabrielson, Yibin Wang
& David A Kass Published online: 23 January 2005|doi:10.1038/nm1175 Abstract|Full text|PDF
(797K)
|Supplementary Information See also:News and Views by Mendelsohn
Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factorpp223 - 227 Vera Jankowski, Markus Tölle, Raymond Vanholder, Gilbert Schönfelder, Markus van der Giet, Lars Henning, Hartmut Schlüter, Martin Paul, Walter Zidek
& Joachim Jankowski Published online: 23 January 2005|doi:10.1038/nm1188 Abstract|Full text|PDF
(360K)
|Supplementary Information
Human embryonic stem cells express an immunogenic nonhuman sialic acidpp228 - 232 Maria J Martin, Alysson Muotri, Fred Gage
& Ajit Varki Published online: 30 January 2005|doi:10.1038/nm1181 Abstract|Full text|PDF
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ERRATUM: Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathwayp233 A Insinga, S Monestiroli, S Ronzoni, V Gelmetti, F Marchesi, A Viale, L Altucci, C Nervi, S Minucci
& P G Pelicci doi:10.1038/nm0205-233a Full text|PDF
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ERRATUM: Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 genep233 W Zhang, H Yang, X Kong, S Mohapatra, H San Juan-Vergara, G Hellermann, S Behera, R Singam, R F Lockey
& S S Mohapatra doi:10.1038/nm0205-233b Full text|PDF
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ERRATUM: The clock gene Per2 influences the glutamatergic system and modulates alcohol consumptionp233 R Spanagel, G Pendyala, C Abarca, T Zghoul, C Sanchis-Segura, M C Magnone, J Lascorz, M Depner, D Holzberg, M Soyka, S Schreiber, F Matsuda, M Lathrop, G Schumann
& U Albrecht doi:10.1038/nm0205-233c Full text|PDF
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3-integrin-deficient- mice is associated with enhanced TGF-
B
