Cholesterol, racial variation and targeted medicines
Eric J Topol
Eric J. Topol is at the Cleveland Clinic Foundation and Cleveland Clinic Lerner Collge of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, USA. topole@ccf.org
One in 50 African-Americans have nonsense mutations in a gene that regulates cholesterol levels, PCSK9, accounting for a substantial lowering of blood LDL-cholesterol.
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