Jean-François Bach is at the Institut National de la Santé et de la Recherche Médicale, Paris, France 75015. bach@necker.fr
Autoimmune disease is set in motion by certain triggers, one of which now comes to light in a mouse model of type 1 diabetes. Signaling through Toll-like receptors, known for receiving signals from viruses and bacteria, initiates the disease (pages 138−145).
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