Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature Medicine 11, 1275 - 1276 (2005)
doi:10.1038/nm1205-1275
A radically twisted lipid regulates vascular death
Lois E H Smith1 & Kip M Connor1
- The authors are at the Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. e-mail: lois.smith@childrens.harvard.edu
Abstract
Maintenance of the retinal vasculature protects against proliferative retinopathy and blindness. Lipids and free radicals together modulate vascular stability through regulation of antiangiogenic proteins (pages 1339–1345).
Regulated development of blood vessels in the retina is vital for the preservation of vision. Retinal neovascularization, resulting in bleeding and retinal detachment, is a major cause of blindness in retinopathy of prematurity (ROP), diabetic retinopathy and age-related macular degeneration.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1?dependent microvascular degenerationNature Medicine Article (01 Dec 2005)
Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesisNature Medicine Letter (01 Jul 2007)
