Nature Medicine 11, 1188 - 1196 (2005)
Published online: 16 October 2005; | doi:10.1038/nm1307
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivoJuhua Chen, Payaningal R Somanath, Olga Razorenova, William S Chen, Nissim Hay, Paul Bornstein
& Tatiana V Byzova Supplementary Fig. 1 (pdf 280K)
Akt1 is the major Akt isoform in vascular cells. Supplementary Fig. 2 (pdf 340K)
Characteristics of vasculature in Akt1 null mice. Supplementary Fig. 3 (pdf 168K)
Absence of Akt1 results in impaired collagen matrix organization. Supplementary Fig. 4 (pdf 268K)
Tumor vasculature and TSP-1 expression are inversely related. Supplementary Fig. 5 (pdf 72K)
Basal levels of eNOS phosphorylation is reduced in Akt1-/- endothelial cells (EC). Supplementary Fig. 6 (pdf 276K)
Reduced vascular maturation in eNOS null mice. Supplementary Methods (pdf 36K)
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