Nature Medicine 11, 1088 - 1095 (2005)
Published online: 11 September 2005; | doi:10.1038/nm1298
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degenerationMasahiro Waza, Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, Chen Sang, Fumiaki Tanaka, Akira Inukai, Manabu Doyu
& Gen Sobue Supplementary Fig. 1 (pdf 156K) Effect of 17-AAG on th expression of mutant AR under the inhibition of the heat-shock response. Supplementary Fig. 2 (pdf 364K) The hematological examination of male AR-97Q mice treated with 17-AAG. Supplementary Fig. 3 (pdf 808K) Quantification of large aggregated and soluble monomeric mutant AR protein by filter-trap assay. Supplementary Fig. 4 (pdf 592K) Effect of 17-AAG on the expression of each chaperone in male AR-97Q mice. Supplementary Methods (pdf 152K)
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