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Nature Medicine 11, 1051 - 1052 (2005)
doi:10.1038/nm1005-1051

Hitchhiker's guide to the T cell

Cliona M Rooney1

  1. The author is in the Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA. e-mail: crooney@bcm.edu


A new approach to tumor therapy combines two problematic cancer-fighting tools: tumor-targeted T cells and gene therapy. The T cells deliver a gene therapy vector to tumor cells, ensuring their destruction (pages 1073–1081).


Gene therapy to treat cancer will never reach its full potential without the availability of targeted gene-transfer vectors. Targeting must include specificity at the level of tissue, cells and DNA.

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