Nature Medicine
11, 43 - 49 (2004)
Published online: 12 December 2004; | doi:10.1038/nm1162
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse modelShigetoshi Sano, Keith Syson Chan, Steve Carbajal, John Clifford, Mary Peavey, Kaoru Kiguchi, Satoshi Itami, Brian J Nickoloff
& John DiGiovanniSupplementary Fig. 1 (pdf 726K)
Constitutive action of Stat3 in the uninvolved, adjacent epidermis of psoriatic patients. Supplementary Fig. 2 (pdf 6210K)
Gross skin phenotypes of K5.Stat3C transgenic mice. Supplementary Fig. 3 (pdf 7047K)
Persistent psoriatic lesions in K5.Stat3C mice. Supplementary Fig. 4 (pdf 5096K)
TPA treatment (twice a week for one month) induced psoriatic skin lesions in K5.Stat3C mice (left panel) with histology (right bottom) identical to human psoriasis. Supplementary Fig. 5 (pdf 803K)
Rapid upregulation of epidermal ICAM-1 by tape-stripping is Stat3-dependent.
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