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Letter
Nature Medicine 11, 77–84 (1 January 2005) | doi:10.1038/nm1161
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
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Abstract
Chromatin is a dynamic macromolecular structure epigenetically modified to regulate specific gene expression. Altered chromatin function can lead to aberrant expression of growth regulators and may, ultimately, cause cancer.
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