Nature Medicine
10, 974 - 981 (2004)
Published online: 22 August 2004; | doi:10.1038/nm1094
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasisTatiana V Petrova, Terhi Karpanen, Camilla Norrmén, Russell Mellor, Tomoki Tamakoshi, David Finegold, Robert Ferrell, Dontscho Kerjaschki, Peter Mortimer, Seppo Ylä-Herttuala, Naoyuki Miura
& Kari AlitaloSupplementary Fig. 1 (pdf 311K)
Analysis of lymphatic vasculature in adult Foxc2+/- mice. Supplementary Fig. 2 (pdf 507K)
Normal early development of lymphatic vasculature in Foxc2-/- mice. Supplementary Fig. 3 (pdf 296K)
Abnormal lymphatic patterning and PC/SMC recruitment in the skin of Foxc2-/- embryos. Supplementary Fig. 4 (pdf 379K)
Skin blood vessel development is normal in Foxc2-/- mice. Supplementary Fig. 5 (pdf 581K)
Mural cells associated with lymphatic vessels of Foxc2-/- mice express the PC marker NG2. Supplementary Fig. 6 (pdf 321K)
Pdgfb, Vegfr3, Prox1 and podoplanin are expressed in lymphatic endothelium lacking Foxc2. Supplementary Fig. 7 (pdf 310K)
Genetic relationship between Vegfr3 and Foxc2. Supplementary Fig. 8 (pdf 251K)
Expression pattern of FOXC2. Supplementary Table 1 (pdf 20K)
Use of antibodies against lymphatic endothelial specific markers in different experimental settings. Supplementary Methods (pdf 27K)
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