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September 2004 - Vol 10 No 9
Nature Medicine 10 (2004)
 
Cover image detail
Mutations affecting the forkhead transcription factor FoxC2 are known to underlie lymphedema-distichiasis syndrome. On page 974 of this issue, Petrovaet al. show that FoxC2 is important for lymphatic valve morphogenesis and for keeping lymphatic capillaries free of pericytes. The cover image shows abnormally patterned and enlarged lymphatic vessels in the skin of Foxc2+/−; Vegfr3+/lacZ embryos (visualized by staining for β-galactosidase).
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