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Not asleep, not quite awake

Narcoleptic individuals experience episodes of cataplexy, in which they retain consciousness but have no muscle tone. Consciousness and muscle tone are controlled by distinct brain regions, now delineated by research on narcoleptic dogs.

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Figure 1: Simplified schematic of model for control of arousal.

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Sutcliffe, J., de Lecea, L. Not asleep, not quite awake. Nat Med 10, 673–674 (2004). https://doi.org/10.1038/nm0704-673

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