Caroline J. Small and Stephen R. Bloom are at the Endocrine Unit, and David Carling is at the Endocrine Unit and the MRC Clinical Sciences Centre Cellular Stress Group, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 ONN, UK. dcarling@imperial.ac.uk or s.bloom@imperial.ac.uk
Treatment with -lipoic acid, found naturally in our diets, decreases food intake in rats and keeps them slim by inhibiting AMP activated protein kinase (AMPK) in the hypothalamus. The findings reinforce the emerging status of AMPK as a cellular integrator that senses signals for food intake and whole body energy status (pages 727−733).
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-lipoic acid, found naturally in our diets, decreases food intake in rats and keeps them slim by inhibiting AMP activated protein kinase (AMPK) in the hypothalamus. The findings reinforce the emerging status of AMPK as a cellular integrator that senses signals for food intake and whole body energy status (pages 727−733).
