Francesco Muntoni, Martin Brockington
& Susan C Brown
Francesco Muntoni, Martin Brockington and Susan C. Brown are at the Dubowitz Neuromuscular Centre, Department of Pediatrics, Imperial College, Hammersmith Campus, London, UK. f.muntoni@imperial.ac.k
Several forms of muscular dystrophy are associated with mutations in genes that regulate glycosylation of -dystroglycan. Forced overexpression of one of these genes, LARGE, in mice overcomes the defective glycosylation present in this group of disorders (pages 696−703).
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-dystroglycan. Forced overexpression of one of these genes, LARGE, in mice overcomes the defective glycosylation present in this group of disorders (pages 696−703).
