Mark P. Burns and Karen Duff are at the Nathan Kline Institute, New York University, Orangeburg, New York 10962, USA. duff@nkri.rfmh.org
A single injection of the neurosteroid allopregnanolone can delay the onset of neurological symptoms, decrease neuronal cell death and double the lifespan of mice with Niemann−Pick type C disease (pages 704−711).
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