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Nature Medicine 10, 594–601 (1 June 2004) | doi:10.1038/nm1052

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Pradip K Majumder , Phillip G Febbo , Rachel Bikoff , Raanan Berger , Qi Xue , Louis M McMahon , Judith Manola , James Brugarolas , Timothy J McDonnell , Todd R Golub , Massimo Loda , Heidi A Lane & William R Sellers