Nature Medicine
10, 1336 - 1343 (2004)
Published online: 14 November 2004; | doi:10.1038/nm1132
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stressNorbert Frey, Tomasa Barrientos, John M Shelton, Derk Frank, Hartmut Rütten, Doris Gehring, Christian Kuhn, Matthias Lutz, Beverly Rothermel, Rhonda Bassel-Duby, James A Richardson, Hugo A Katus, Joseph A Hill
& Eric N OlsonSupplementary Fig. 1 (pdf 93K)
Smaller cardiomyocytes in calsarcin-deficient hearts. Supplementary Fig. 2 (pdf 38K)
Calsarcin inhibits calcineurin activity in vitro. Supplementary Fig. 3 (pdf 98K)
Calsarcin-1 null/MCIP-transgenic mice display superinduction of ANF-expression. Supplementary Fig. 4 (pdf 46K)
Similar degree of exercise-induced hypertrophy in wild-type and calsarcin mutant hearts Supplementary Table 1 (pdf 113K)
Transthoracic echocardiographic analysis of wild-type and calsarcin mutant hearts Supplementary Table 2 (pdf 144K)
Characterization of left ventricular mechanics by pressure-volume measurements Supplementary Table 3 (pdf 114K)
Sequences of primers used in dot-blot and rea-time PCR experiments Supplementary Methods (pdf 31K)
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