Vitamin A helps gut T cells find their way in the dark
Bengt Johansson-Lindbom
& William W Agace
The authors are in the Section for Immunology, Department of Cell and Molecular Biology, Lund University, Lund, Sweden. william.agace@immuno.lu.se
Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.
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