Michael S. Diamond is in the Departments of Medicine, Molecular Microbiology, Pathology & Immunology; and Robyn S. Klein is in the Departments of Medicine, Pathology & Immunology and Anatomy & Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110 USA. diamond@borcim.wustl.edu
A study in mice traces the path of West Nile virus into the brain. Viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier (pages 1366−1373).
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